Learn About Astragalus Benefits and Research

What Is Astragalus and Where Does It Come From?

Astragalus is a plant that has been used in traditional Chinese medicine for thousands of years. The herb comes from the root of the Astragalus membranaceus plant, which grows in northern regions of China and Mongolia. The root is the part people harvest and use for health purposes. In traditional Chinese medicine, practitioners have valued astragalus for over 2,000 years, often combining it with other herbs in formulas designed to support overall wellness.

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The plant itself is a perennial legume, meaning it's related to beans and peas. Astragalus roots are typically dried and processed into various forms—powders, capsules, tablets, teas, or liquid extracts. These different forms allow people to incorporate the herb into their daily routines in different ways. Some people brew dried astragalus root as a tea, while others prefer capsules for convenience. The herb has a slightly sweet taste, which is why it's sometimes used in soups and broths in Asian cuisine.

The active compounds in astragalus that researchers have studied include polysaccharides, flavonoids, and saponins. These are natural chemicals found in the plant that may have various effects on the body. Scientists are particularly interested in polysaccharides, which make up a significant portion of astragalus root. Understanding what's actually in astragalus helps explain why researchers have become interested in studying how it might affect human health.

Today, astragalus is available as a dietary supplement in health food stores and online retailers throughout North America and Europe. It remains more commonly used in Asian countries where it has deeper cultural and historical roots. The popularity of astragalus in Western countries has grown over the past two decades as more research has been conducted and more people have learned about traditional uses of the herb.

Practical Takeaway: Astragalus is an ancient herb from the legume family with a documented history of use in traditional medicine. Knowing its origin and different available forms can help you understand what you're purchasing and how to use it appropriately.

Research on Astragalus and Immune Function

One of the primary areas where researchers have studied astragalus is its potential relationship with immune system function. Several scientific studies have examined how astragalus compounds might interact with immune cells in the body. A 2021 review published in the journal Molecules analyzed multiple studies and found evidence that polysaccharides from astragalus may stimulate certain types of white blood cells, including macrophages and natural killer cells. These are immune cells that help protect the body from infections and abnormal cell growth.

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In laboratory studies, researchers have observed that astragalus extracts can increase the activity of these immune cells in test tubes. However, laboratory results don't always translate directly to effects in living people. When researchers moved to human studies, the results became more mixed. Some studies showed that people taking astragalus supplements had modest improvements in certain immune markers, while others showed minimal or no effect. The variation in results may be due to differences in study design, the type and dose of astragalus used, and the health status of study participants.

A 2019 study published in Evidence-Based Complementary and Alternative Medicine examined astragalus in combination with other herbs for people with specific health conditions. The researchers found that participants who took the herbal combination showed some improvements in immune markers compared to a control group. However, the study was relatively small, involving fewer than 100 participants, and it looked at a combination of herbs rather than astragalus alone.

Researchers emphasize that while astragalus shows promise in laboratory and some human studies, more rigorous research is needed before making strong claims about its effects on immune function. The quality of available research varies, and many studies have been conducted outside Western research institutions, which can make it harder to assess methodology and reliability. It's important to understand that observing an effect in a laboratory or in a small study doesn't mean the same effect will occur reliably in all people.

Practical Takeaway: Research suggests astragalus may have some relationship with immune function, but results are inconsistent across studies. Current evidence is suggestive rather than definitive, meaning more research would help clarify actual effects in people.

Astragalus and Telomeres: What the Research Shows

Telomeres are tiny structures at the ends of chromosomes in your cells. They're often compared to the plastic tips on shoelaces because they protect the ends of chromosomes. Each time a cell divides, telomeres get shorter. Eventually, when telomeres become too short, cells can no longer divide and may die or stop functioning properly. This process is thought to be connected to aging at the cellular level. Some researchers have explored whether astragalus might support telomere length or function.

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A landmark study published in 2011 in the Journal of Gerontology examined astragalus extract and telomerase, an enzyme that helps maintain telomere length. The study involved a relatively small group of participants and found that those who took an astragalus extract showed an increase in telomerase activity compared to a control group. Specifically, the telomerase activity increased by about 40 percent in the astragalus group. This was an interesting finding that generated interest among researchers studying aging and cellular health.

However, subsequent research hasn't consistently replicated these results. Other studies have tried to examine the relationship between astragalus and telomere length with varying outcomes. Some studies found modest effects, while others found no significant differences between astragalus and control groups. The reasons for these inconsistent results could relate to differences in study participants, dosages, duration of treatment, and how telomere length was measured.

It's also important to understand that even if astragalus could support telomere length, scientists still don't fully understand what that would mean for actual health outcomes. Telomere length is a marker that scientists study, but having longer telomeres isn't guaranteed to mean better health or slower aging. The relationship between telomere length and overall lifespan and health in humans remains an active area of research. Additionally, many factors influence telomere length—including stress, exercise, diet, and genetics—making it difficult to isolate the effect of any single supplement.

Practical Takeaway: Some studies suggest astragalus may influence telomerase activity, but evidence is mixed and unclear what this might mean for human health and aging. This remains an area where more research would help clarify the actual significance of these cellular changes.

Potential Uses of Astragalus in Traditional and Modern Contexts

In traditional Chinese medicine, practitioners have used astragalus for a wide range of conditions. It was traditionally considered a "qi tonic," where "qi" (pronounced "chee") refers to vital life force or energy in Chinese medical theory. Traditional uses included supporting energy levels, promoting recovery after illness, and supporting the body's general defense mechanisms. Some practitioners used it for people experiencing fatigue or weakness after recovery from illness. Others incorporated it into formulas for people with chronic conditions or those seeking to support overall wellness.

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In modern contexts, supplement manufacturers market astragalus for several potential uses. These commonly include supporting immune function during cold and flu season, promoting energy and stamina, supporting cardiovascular health, and supporting kidney function. Some products combine astragalus with other herbs to create formulas targeting specific health concerns. It's important to note that listing these uses doesn't mean the scientific evidence definitively supports them—it indicates these are areas where people use astragalus and where some preliminary research exists.

Several research directions have emerged in Western studies. Some researchers have examined astragalus for people undergoing certain cancer treatments, where preliminary studies suggest it might support quality of life markers and immune function during treatment. Other research has explored astragalus for people with specific kidney concerns, diabetes-related conditions, and heart health. A small number of studies have looked at astragalus combined with conventional treatments, though conclusions remain preliminary.

Athletic performance represents another area where some people use astragalus. The reasoning is based on traditional uses for supporting energy and stamina, combined with the idea that it might support recovery after exercise. However, scientific studies specifically examining astragalus and athletic performance are limited. A few small studies have explored this question, with mixed results that don't provide clear evidence either supporting or refuting benefits for athletic populations.

Practical Takeaway: Astragalus has many traditional uses and is marketed for various